Experienced, Specialised & Dynamic Teams Serving Healthcare
Multiple myeloma – Haematology
EPIC’s specialised teams in Haematology, support one of the most widely used treatment options for Multiple myeloma.
Multiple myeloma is a cancer of the plasma cells, which are a type of white blood cell made in the bone marrow. Healthy plasma cells help you fight infections by making antibodies that recognize and attack germs. In multiple myeloma, cancerous plasma cells accumulate in the bone marrow and crowd out healthy blood cells. About 361 people are diagnosed with myeloma in Ireland every year. There are several treatments that can slow down and control multiple myeloma very well. In 2019, around 2,000 people were living with myeloma in Ireland.
Hereditary angioedema (HAE) – Immunology / Rare Disease
EPIC’s specialised teams in Immunology, support an innovative new treatment option for HAE.
HAE is a rare genetic disease characterised by recurrent sudden attacks of oedema of the skin or the mucous membranes. HAE affects between 1 in 10,000 and 1 in 50,000 people.
HAE is caused by an inherited deficiency of C1-esterase inhibitor (C1-INH), a protein which has a regulatory role in the classic complement pathway and in the coagulation, fibrinolytic, and kallikrein–kinin (contact-system) cascades. In HAE, C1-INH deficiency results in an increased release of the peptide hormone bradykinin, the key mediator of HAE symptoms. Bradykinin is released locally in response to trauma, injury or other triggers, in the affected area. It binds to the bradykinin B2 receptor at the thin layer of endothelial cells that line the interior surface of the blood vessel wall, causing the vessels to dilate and become more permeable. As a result, fluid passes into the surrounding tissue and leads to oedema formation.
Oncology & Haematology – Unlicensed Medicines
Epicpharms specialised team provides Medical Science Liaison and Market Access support for a no. of unlicensed medicines in the Haematology Oncology area.
Oncology & Haematology – Supportive Care
Epicpharms specialised team distribute and promote a no. of Supportive Care Medicines and Medical Devices to Healthcare Professionals and ultimately patients undergoing treatment for cancer.